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产品目录

重组人ABCB5(ATP结合盒蛋白亚家族B成员5)图片
产品货号:
JN0960
中文名称:
重组人ABCB5(ATP结合盒蛋白亚家族B成员5)
英文名称:
Recombinant Human ATP-binding cassette sub-family B member 5
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Ile141-Val247在N端含Trx标签。

ABCB5质量控制:>95%(还原性SDS-PAGE)

ABCB5制剂:冻干品

ABCB5保存
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

ABCB5复溶
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。

关于ABCB5
ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein. ABCB5 is principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progenitor cell fusion and mediate chemotherapeutic drug resistance in stem-like tumor cell subpopulations in human malignant melanoma. It is commonly over-expressed on circulating melanoma tumour cells. Furthermore, the ABCB5+ melanoma- initiating cells were demonstrated to express FLT1 (VEGFR1) receptor tyrosine kinase which was functionally required for efficient xenograft tumor formation, as demonstrated by shRNA knockdown experiments.
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